R454C (Opteon™️ XL20) is a Low GWP hydrofluoro-olefin (HFO) based refrigerant replacement for R404A and R22.
R454C is a close match to R22 based technology, but it is also a valid solution for R404A equipment.
With a GWP 148, it falls under the important maximum value of 150 in the F-Gas regulation. Classified as mildly flammable (A2L), R454C allows much higher charge sizes than other flammable refrigerants and can be safely used by following the applicable codes and standards.